Separation &

Zaiput Flow Technologies is dedicated to bringing innovative tools for continuous and batch separation processes to the market. Our products include liquid-liquid/liquid-gas separators, back pressure regulators, and multi-stage extraction platforms that are scalable, modular, and continuous. Whether you work in academia or industry, if you work in batch or continuous flow, we believe that our products will help to streamline your work, enable new approaches and allow you to harvest the power of chemistry.

Liquid-Liquid/Gas-Liquid Separators

  • 3 modules accommodate 0–3000 mL/min
  • Small internal volume
  • Excellent chemical resistance
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Z-FOX Batch Extraction Platform

  • Integrated liquid-liquid extraction for batch applications
  • High throughput for pilot and production scale
  • Increase plant capacity with continuous extraction
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Back Pressure Regulators

  • Pressurize streams to any set point up to 2 MPa
  • Work well with single/multi-phase flows
  • Excellent chemical resistance
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Multistage Extraction

  • Only existing tool for bench top CC-LLE process development
  • Quick and direct scale-up
  • Addresses the most difficult extractions
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Zaiput in Space

As space travel and extraterrestrial habitation become a reality, it is becoming important to be able synthesize chemicals in space. Liquid separation is a key step in liquid extraction, one of the common steps in pharmaceutical production.

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News & Events


In an article published just over 10 years ago now, a roundtable from top companies in the pharmaceutical and fine chemical industries highlighted some of the many needs for making chemical manufacturing greener and more sustainable.  

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We’re hiring!

For more information, visit our Careers page!

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ChemSpec Webinar

Hybrid batch flow processes, is this the future? A webinar led by our CEO, Andrea Adamo, on the future of separation.

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In-line Purification Review

Nopphon Weeranoppanant and Andrea Adamo, In-Line Purification: A Key Component to Facilitate Drug Synthesis and Process Development in Medicinal Chemistry, ACS Med. Chem. Lett., Dec 2019.

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Article featuring Zaiput’s multistage platform

Continuous Flow Synthesis of Methyl Oximino Acetoacetate: Accessing Greener Purification Methods with Inline Liquid–Liquid Extraction and Membrane Separation Technology

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Webinar on Flow/Batch Separation

Liquid-Liquid/Gas-Liquid Separation for Continuous and Batch Chemical Processing

Date: Now On-Demand, originally recorded November 27, 2018
Duration: 60-minutes

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Science article featuring design concepts from our CEO and leveraging Zaiput technology

Congratulations to our Founder and CEO Andrea Adamo and his colleagues at Massachusetts Institute of Technology for this great publication!

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Announcing BPR-1000

BPR-1000 is our newest back pressure regulator for flow chemists with the same robust, easy to use design of BPR-10 but allowing high accuracy for flow rates up to 1000 ml/min. 

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SEP-3000 is here!

Our newest separator, SEP-3000, makes scaling from bench to production seamless.

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"We have been using the ZAIPUT© technology for more than 3 years now. It proves to be an efficient, safe, reliable, simple to use, perfectly scalable device, serving our large variety of hazardous and corrosive chemistries. It's an ideal tool for Liquid/Liquid or Liquid/Gas separation challenges."
Laurent Pichon President, MEPI, France
"A much appreciated device in our continuous flow development labs."
Joerg Sedelmeier, PhD Principal Scientist, Roche
"Zaiput's technology fundamentally changes the risk/benefit analysis of including or excluding an extraction step in a manufacture process. It does this by offering the opportunity to sidestep traditional extraction issues (emulsions, extended layer separations, and reproducibility) while harnessing extraction's inherent ability to control critical quality attributes."
John C. Roberts, PhD Director Corporate Relations, MIT
"We have been very pleased with the liquid-liquid separator from Zaiput. This device fulfills an important role in downstream processing of our flow chemistry equipment. "
Professor Steven Ley University of Cambridge
"The back pressure regulator works incredibly well for our process! The regulator we were using previously was a single stage spring-loaded regulator, and it was giving us terrible stop-and-go flow so we looked to your device to help fix this. Since we are operating slightly outside of the flow rate ranges that you have tested, there was some question as to whether your device would function properly for our process. Well the answer is yes! We have experienced absolutely no “chatter” or stop-and-go flow. I have successfully achieved pressures up to 100 psi, and the setpoint does not drift over time as we experienced with the spring loaded regulator. "
Trevor Rosensohn Chemical Engineer, NALAS Engineering Services, Inc.
"We have been using Zaiput liquid-liquid separators for efficient in-line phase separation in several projects successfully. They allow us to design multi-step sequences, to be run in continuous fashion for enabling scale-up preparations."
Carlos Mateos, Ph.D. Eli Lilly and Co.
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Our technology is used by The Top Pharmaceutical Companies Worldwide and has also been featured in 70+ publications, including: